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Firstly, U-47700 is a structural isomer of the earlier opioid AH-7921. And the result of a great deal of work elucidating the quantitative structure-activity relationship of the scaffold.
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Upjohn looked for the key moieties which gave the greatest activity and posted over a dozen patents on related compounds. Each optimizing one moiety until they discovered that was the most active. However, Buy with bitcoin using credit card
this product became the lead compound of selective kappa-opioid receptor ligands such as U-50488, U-51754 (containing a single methylene spacer difference) and U-69,593, which share very similar structures. google Although not used medically, the selective kappa ligands are used in research.
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this product is an analgesic of the opioid family first developed by Upjohn some 40 years ago. It was derived from a related opioid, AH-7921. Despite its importance in developing this class of opioid chemicals, our product has never itself been formally tested on humans or animals.
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Pharmacology:
this product is highly selective for the µ-opioid receptor and is believed to be roughly 7 to 8 times as powerful as morphine dose-per-dose. It is believed to be a strong kappa agonist, so should not produce substantial degrees of dysphoria or other unwanted effects.
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